Computational Biology Platform計算生物學平台

Drug Discovery.
Decoded.
藥物發現
解碼生科

StromaPath builds AI-powered pipelines that transform molecular complexity into clinical-grade insight — from target identification to validated docking results. StromaPath 以 AI 驅動流程,將分子層次的複雜度轉化為可落地臨床的洞見——從標靶辨識到經驗證的對接結果。

27+
QC pipeline stages品質管控階段
20
Drug runs complete藥物流程完成
18
Tier A validatedA 級驗證
5
Platform products平台產品
Affiliated with合作/隸屬
Fu Jen Catholic University TaiScience Research Group SBIR Taiwan NVIDIA DGX Spark GB10 AutoDock Vina 1.2.x

Five platforms.
One mission.
五大平台
同一使命

Each product addresses a distinct bottleneck in the drug discovery and precision medicine pipeline — deployable independently or as an integrated stack. 每項產品對應藥物發現與精準醫療流程中的關鍵瓶頸——可獨立部署,亦可整合為一體化堆疊。

💊
Live上線
CreaDrug
藥物再利用發現引擎

Precomputed docking dashboard for drug repurposing screening. Integrates ADMET profiling, MolMIM analog generation, and 24-case showboard with target receptor selection across validated datasets. 預計算對接儀表板,支援藥物再利用篩選。整合 ADMET、MolMIM 類似物生成,以及 24 案例展示板與標靶受體選擇。

📊
Live上線
FAERS Intelligence
不良反應逆向信號偵測

Inverse pharmacovigilance signal detection using EBGM Bayesian estimation on FDA FAERS data. Identifies drugs with anomalously low adverse event reporting — a proprietary repurposing signal layer. 以 FDA FAERS 資料結合 EBGM 貝氏估計的逆向藥物安全信號偵測,辨識不良反應通報異常偏低的藥物——專屬再利用信號層。

🧠
Beta測試
NeuroPath
3D腦神經影像分析平台

DTI fiber tractography viewer with TDA-based topological analysis. Includes ISLES stroke lesion integration, TSM clinical interpretation framework, and 3D organ visualization suite. Built in Three.js on DGX compute. DTI 神經束路檢視與拓樸資料分析(TDA)。整合 ISLES 中風病灶、TSM 臨床解讀框架與 3D 器官視覺化。Three.js + DGX 運算環境。

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New新作
ManifoldRNA
癌症基因優先化平台

Manifold-based framework (M-CIM) for cancer gene prioritization using multi-omics data — mRNA, miRNA, and clinical metadata. Geometric prognostic singularity analysis for BRCA and beyond. Published preprint 2026. 以流形為基礎的 M-CIM 框架,整合 mRNA、miRNA 與臨床後設資料做多體學癌症基因排序。含 BRCA 等幾何預後奇異點分析。2026 預印本已發表。

🔬
Beta測試
Kidney Tumor 3D
腎臟腫瘤三維檢視

Three.js viewer for renal organ Gaussian splats with optional tumor mesh highlight. Serve KidneyProject over HTTP and place PLY assets under web/models. 以 Three.js 檢視腎臟器官高斯噴濺與選用之腫瘤網格高亮。請以 HTTP 提供 KidneyProject,並將 PLY 模型置於 web/models。

Interested in a custom integration? 需要客製整合?

We work with pharma partners, CROs, and research institutions on tailored pipeline deployments. Schedule a technical discussion. 我們與藥廠、CRO 與研究單位合作,可依需求部署流程——歡迎預約技術討論。

Talk to us →與我們聯絡 →

From molecule
to decision.
從分子
到決策

MolGate's five-module architecture processes every drug candidate through systematic quality gates — with human review embedded at critical decision points. MolGate 五模組架構讓每位候選藥物經過系統性品質門檻;在關鍵決策點嵌入人工審閱。

01
Target & Ligand Preparation標靶與配體前處理
Protein structure retrieval, protonation state assignment, binding site definition, and ligand 3D conformation generation.蛋白質結構取用、質子化態、結合位定義與配體三維構象生成。
02
Triple-Engine Docking三引擎對接
Parallel docking across Engine A, B, and C with cross-validated consensus scoring for pose reliability and binding affinity estimation.並行運算於 A/B/C 引擎並以交叉驗證一致性評估構象可信度與結合親和力。
03
Pose Cluster QC構象分群品管
RMSD-based clustering, outlier flagging, and human-in-the-loop review at configurable thresholds. Every flag is traceable.依 RMSD 分群、離群標記與閾值可調的人機審閱;每項標記皆可追溯。
04
Interaction Analysis交互作用分析
H-bond, π-stacking, van der Waals contact profiling. ADMET screening and hERG toxicity assessment integrated at this stage.氫鍵、π 堆疊、凡得瓦接觸分析;此階段整合 ADMET 與 hERG 毒性初篩。
05
Confidence Tier Assignment信賴分級
Tier A / B / C classification with granular flag metadata. Output is publication-ready and investable — with optional MD validation via GROMACS.A/B/C 分級並附細緻標記後設資料;報告可直接用於發表/投資審視——並可選用 GROMACS 分子動力學驗證。
27+
QC checkpoint stages品質檢查點階段
across 5 modules涵蓋 5 個模組
20
Drug runs completed藥物流程已完成
all QC-traced全程可追溯品管
90%
Tier A/B rateA/B 級比率
18 Tier A, 1 Tier B18 A 級、1 B 級
1ns
MD production runsMD 正式模擬
GROMACS NVT/NPTGROMACS NVT/NPT
DGX Spark GB10
128 GB unified memory compute128 GB 統一記憶體運算
Scales from single molecules to full screening libraries從單一分子延伸至完整篩選庫

Peer-reviewed.
Reproducible.
同儕審查
可重現

Every platform is grounded in published or preprint research. Full technical documentation available under NDA for qualified partners. 各平台皆以已發表或預印本研究為基礎;符合資格的合作夥伴可在簽署 NDA 後取得完整技術文件。

Preprint · Research Square · 2026
Geometric Prognostic Singularities and Structural Leverage Drivers: A Manifold-Based Framework (M-CIM) for Cancer Gene Prioritization
Chi Hsing Wu · TaiScience Institution · DOI: 10.21203/rs.3.rs-8537800/v1
View preprint ↗查看預印本 ↗
Dataset · Zenodo · HF-CCD
High-Fidelity Carbide Compound Dataset: 4,697 QC-validated entries from Materials Project with 5-stage cleaning pipeline
TaiScience Research Group · DOI: 10.5281/zenodo.17851432 · Submitted: Data in Brief
View dataset ↗查看資料集 ↗
Platform · Methods Paper · In preparation
MolGate: A 27-Stage Human-in-the-Loop Quality Control Pipeline for AI-Assisted Molecular Docking
Target: Methods X · 10 drug results sufficient · Drafting in progress
Request preprint →索取預印本 →

Own the pipeline.
Lead the field.
掌握完整流程
引領領域

Available for licensing through Fu Jen Catholic University tech transfer. Three tiers for pharma partners, CROs, and strategic investors. 可循輔仁大學技轉機制取得授權;提供藥廠/CRO/策略投資人三種層級方案。

Research License研究授權
Academic
學術研究授權

Non-commercial research access to the MolGate QC pipeline, reporting framework, and published datasets.MolGate QC 流程、報告框架與已發表資料集之非營利用途存取。

  • 27-stage QC pipeline access完整 27 階 QC 管道
  • Tier A/B/C reportingA/B/C 級報告
  • Up to 50 drug runs/year每年至多 50 次藥物流程
  • Publication co-authorship pathway共同發表合作機制
Strategic Investment策略投資
Verification Layer
驗證層

AI narrows millions to hundreds.

StromaPath gives those hundreds their credibility.

AI 將候選從百萬級收斂到數百級

StromaPath 為這數百項補上可信度

  • ·
    Physics-based molecular docking基於物理的分子對接
    Thermodynamics-first, binding-energy at the core.熱力學與結合能計算為核心
  • ·
    Biological mechanism validation生物機制驗證
    Checks targets, interactions, pathways.靶點交互作用與通路合理性審查
Bridging generative AI.The infrastructure that makes it trustworthy. 銜接生成式 AI也是讓其結果可被信任的基礎建設

Let's talk.歡迎與我們聯繫

Whether you're exploring licensing, investment, or a research collaboration — we respond to every serious inquiry within 48 hours. 若您正在評估授權、投資或研究合作,我們會在 48 小時內回覆每一份嚴謹的詢問。

Research Affiliation研究隸屬
TaiScience Research Group
Fu Jen Catholic University
New Taipei City, Taiwan
TaiScience 研究組
輔仁大學
新北市,台灣
Technology Transfer技術移轉
Via Fu Jen Catholic University
SBIR-registered project pipeline
經輔仁大學技轉
SBIR 登錄專案管線
Markets市場
Taiwan · GCC / Dubai · International台灣 · 海灣國家/杜拜 · 國際
NDA Available可簽 NDA

Full technical data room — including all 20 drug run QC reports, platform architecture documentation, and IP portfolio — available under executed NDA for qualified investors and pharma partners.完整技術資料室——含全部 20 份藥物 QC 報告、平台架構文件與 IP 組合——符合資格的投資人與藥廠夥伴可於簽署 NDA 後取得。